Mechanobiology in Epithelial
3D Tissue Constructs


Combining Image Restoration and Traction Force Microscopy to Study Extracellular Matrix-Dependent Keratin Filament Network Plasticity

Yoon S, Windoffer R, Kozyrina AN, Piskova T, Di Russo J and Leube RE

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Quantitative mapping of keratin networks in 3D commentary

Windoffer R, Schwarz N, Yoon S, Piskova T, Scholkemper M, Stegmaier J, Bönsch A, Di Russo J, Leube RE

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Keratin filaments mediate the expansion of extra-embryonic membranes in the post-gastrulation mouse embryo

Nahaboo W , Eski SE , Despin-Guitard E, Vermeersch M, Versaevel M , Saykali B, Monteyne D, Gabriele S, Magin TM, Schwarz N , Leube RE, Zwijsen A, Perez-Morga D, Singh SP, Migeotte I

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The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates

Mabrouk MHE, Goetzke R, Abagnale G, Yesilyurt B, Salz L, Cypris O, Glück P, Liesenfelder S, Zeevaert K, Ma Z, Toledo MAS, Li R, Costa IG,
Lampert A, Pachauri V, Schnakenberg U, Zenke M, Wagner W

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Characterization of Synthetic Tf2 as a NaV1.3 Selective Pharmacological Probe

Israel MR , Dash TS, Bothe SN, Robinson SD, Deuis JR, Craik DJ, Lampert A, Vetter I and Durek T

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Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity

Cann KL, Meents JE, Eswaran VSB, Dohrn MF, Bott R, Maier A, Bialer M, Hautvast P, Erickson A, Rolke R, Rothermel M, Körner J, Kurth I, Lampert A

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Assessing the impact of pain-linked Nav1.7 variants: An example of two variants with no biophysical effect

Hoffmann M, Hersch N, Gerlach S, Dreissen G, Springer R, Merkel R, Csiszár A and Hoffmann B 

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Growth, lifetime, directional movement and myosindependent motility of mutant keratin granules in cultured cells

Lehmann SM, Leube RE, Windoffer R

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Mechanism underlying hooked resurgent-like tail currents induced by an insecticide in human cardiac Nav1.5

Thull S, Neacsu C, O'Reilly AO, Bothe S, Hausmann R, Huth T, Meents J, Lampert A

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Human sensory neurons derived from pluripotent stem cells for disease modelling and personalized medicine

Lampert A, Bennett DL, McDermott LA, Neureiter A, Eberhardt E, Winner B, Zenke M

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Stretchable electrical cell-substrate impedance sensor platform for monitoring cell monolayers under strain

Zhou C, Bette S, Babendreyer A, Hoffmann C, Gerlach S, Kremers T, Ludwig A, Hoffmann B, Merkel R, Uhlig S, Schnakenberg U

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Mechanical Regulation of Epithelial Tissue Homeostasis

Kaliman S, Hubert M, Wollnik C, Nuić L, Vurnek D, Gehrer S, Lovrić J, Dudziak D, Rehfeldt F and Smith AS

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Complex Size and Surface Charge Determine Nucleic Acid Transfer by Fusogenic Liposomes

Hoffmann M, Hersch N, Gerlach S, Dreissen G, Springer R, Merkel R, Csiszár A and Hoffmann B 

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Controlling Structure with Injectable Biomaterials to Better Mimic Tissue Heterogeneity and Anisotropy

Babu S, Albertino F, Anarkoli AO and De Laporte L

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From Microspikes to Stress Fibers: Actin Remodeling in Breast Acini Drives Myosin II-Mediated Basement Membrane Invasion

Eschenbruch J, Dreissen G, Springer R, Konrad J, Merkel R, Hoffmann B and Noetzel E

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How Mechanical Forces Change the Human Endometrium during the Menstrual Cycle in Preparation for Embryo Implantation

Sternberg AK, Buck VU, Classen-Linke I and Leube RE

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Skin under Strain: From Epithelial Model Tissues to Adult Epithelia

Püllen R, Konrad J, Merkel R and Hoffmann B

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Multiscale 3D Bioprinting by Nozzle-Free Acoustic Droplet Ejection

Jentsch S, Nasehi R, Kuckelkorn C, Gundert B, Aveic S and Fischer H

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Hemidesmosome-Related Keratin Filament Bundling and Nucleation

Moch M and Leube RE

Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids

Buck VU, Kohlen MT, Sternberg AK, Rösing B, Neulen J , Leube RE, Classen-Linke I

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Cell Force-Driven Basement Membrane Disruption Fuels EGF- and Stiffness-Induced Invasive Cell Dissemination from Benign Breast Gland Acini

Gaiko-Shcherbak A, Eschenbruch J, Kronenberg NM, Teske M, Wolters B, Springer R, Gather MC, Merkel R, Hoffmann B, Noetzel E

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Regulation of keratin network dynamics by the mechanical properties of the environment in migrating cells

Pora A, Yoon S, Dreissen G, Hoffmann B, Merkel R, Windoffer R and Leube RE

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Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells

Babendreyer A, Rojas-Gonzalez DM, Giese AA, Fellendorf S, Düsterhöft S, Mela P and Ludwig A

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Mechanobiology of Epithelia: From the Perspective of Extracellular Matrix Heterogeneity

Kozyrina AN, Piskova T and Di Russo J

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Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes

Bornes L, Windoffer R, Leube RE, Morgner J, van Rheenen J

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Cell Mechanics in Embryoid Bodies

Zeevaert K, Elsafi Mabrouk MH, Wagner W and Goetzke R

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Model for Bundling of Keratin Intermediate Filaments

Haimov E, Windoffer R, Leube RE, Urbakh M, Kozlov M

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Choosing the Right Differentiation Medium to Develop Mucociliary Phenotype of Primary Nasal Epithelial Cells In Vitro

Luengen AE, Kniebs C, Buhl EM, Cornelissen CG, Schmitz-Rode T, Jockenhoevel S, Thiebes AL

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Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells

Hollmann J, Brecht J, Goetzke R, Franzen J, Selich A, Schmidt M, Eipel M, Ostrowska A, Hapala J, Fernandez-Rebollo E, Müller-Newen G,  Rothe M, Eggermann T, Zenke M and Wagner W

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Different Frequency of Cyclic Tensile Strain Relates to Anabolic/Catabolic Conditions Consistent with Immunohistochemical Staining Intensity in Tenocytes

Kubo Y, Hoffmann B, Goltz K, Schnakenberg U, Jahr H, Merkel R, SchulzeTanzil G, Pufe T and Tohidnezhad M

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Why do epithelia display heterogeneity? Bridging physical and biological concepts

Vishwakarma M and Di Russo J

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Cellular responses to beating hydrogels to investigate mechanotransduction

Chandorkar Y, Castro Nava A, Schweizerhof S, Van Dongen M, Haraszti T, Köhler J, Zhang H, Windoffer R, Mourran A, Möller M, De Laporte L

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Keratin intermediate filaments: intermediaries of epithelial cell migration

Yoon S, Leube RE

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β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5

Maroni M, Körner J, Schüttler J, Winner B, Lampert A, Eberhardt E

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Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels

Goetzke R, Keijdener H, Franzen J, Ostrowska A, Nüchtern S, Mela P and Wagner W

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