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Mechanobiology in Epithelial
3D Tissue Constructs


Wednesday, November 18, 2020














Mechanical feedback cycles determine the function and self-organization of cells and tissues in space and time

MEƎT's research concentrates on major aspects of epithelial tissue physiology by investigating force-guided differentiation, cohesion and penetration of epithelial spheroids (project area A), force-dependent homeostasis, responses and sensation in epidermal equivalents (project area B), and force-induced signaling, inflammation and cilia function in lung tissue models (project area C). The work is enabled and driven by a comprehensive basis of technological know-how (project area D).

PROJECT AREA A
Mechanobiology of lumen-bearing tubules and spheroids
PROJECT AREA D
Tools in mechanobiology of 3D tissues
PROJECT AREA B
Mechanical properties of stratified 3D tissue constructs
PROJECT AREA C
Mechanical cross-talk between tissues and the external environment